2013

Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity

Ryutaro Satou, Akimasa Miyanaga, Hiroki Ozawa, Nobutaka Funa, Yohei Katsuyama, Ken-ichi Miyazono, Masaru Tanokura, Yasuo Ohnishi, Sueharu Horinouchi.

J. Biol. Chem., 288, 34146-34157. (2013)

Complex structure of the DNA-binding domain of AdpA, the global transcription factor in Streptomyces griseus, and a target duplex DNA reveals the structural basis of its tolerant DNA sequence specificity

Ming Dong Yao, Jun Ohtsuka, Koji Nagata, Ken-ichi Miyazono, Yuehua Zhi, Yasuo Ohnishi, Masaru Tanokura.

J. Biol. Chem., 288, 31019-31029. (2013)

Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics

Geoffrey P. Horsman, Anna Lechner, Yasuo Ohnishi, Bradley S. Moore, Ben Shen.

Biochemistry, 52, 5217–5224. (2013)

4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one Synthesis by a Type III Polyketide Synthase from Rhodospirillum centenum

Takayoshi Awakawa, Yoshinori Sugai, Kanae Otsutomo, Shukun Ren, Shinji Masuda, Yohei Katsuyama, Sueharu Horinouchi, Yasuo Ohnishi.

Chembiochem, 14, 1006-1013. (2013)

An alternative sigma factor governs the principal sigma factor in Streptomyces griseus

Hiroshi Otani, Akiyoshi Higo, Hideaki Nanamiya, Sueharu Horinouchi, Yasuo Ohnishi.

Mol. Microbiol., 87, 1223-1236. (2013)

住所 : 東京都文京区弥生1-1-1東京大学農学部2号館